Cyclin-Dependent Kinase 7 (CDK7) (Middle Region) Peptide
CDK7
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974779
Quick Overview for Cyclin-Dependent Kinase 7 (CDK7) (Middle Region) Peptide (ABIN974779)
Target
CDK7
(Cyclin-Dependent Kinase 7 (CDK7))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDK7 antibody (Catalog #: P100995_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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Background
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CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAK1, CDKN7, MO15, STK1, p39MO15, HCAK
Protein Interaction Partner: CDK2,CDK6,RARA,THRA,VDR,AR,BRCA1,CCNH,CDK1,CDK2,CDK7,E2F1,ERCC2,ERCC3,ESR1,GTF2H1,GTF2H2,GTF2H5,LASP1,MCM7,MNAT1,NEK6,PCGF6,RARA,THRA,VDR,AR,CCNH,CCT2,CDC37,CUX1,E2F1,ERCC3,ERCC5,ESR1,GTF2H1,GTF2H2,GTF2H3,GTF2H4,GTF2H5,HDAC2,HNRNPU,HSP90AB1,KIAA1967,MCM7,MED21,MNAT1,MTA1,POLR2A,RUVBL2,SUPT5H,TCEA1,TP53
Protein Size: 346 -
Molecular Weight
- 39 kDa
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Gene ID
- 1022
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NCBI Accession
- NM_001799, NP_001790
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UniProt
- P50613
Target
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