CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (N-Term) Peptide
CEBPB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CEBPB products
- CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CEBPB antibody (Catalog #: ARP57940_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))
- Background
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CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: C/EBP-beta, CRP2, IL6DBP, LAP, MGC32080, NF-IL6, TCF5
Protein Interaction Partner: DDIT3,EGR1,PRG2,SMAD4,ATF2,ATF4,CAMK2A,CCL3,CEBPA,CEBPB,CEBPD,CEBPG,CREB1,CREBBP,DDIT3,EGFR,EGR1,ELK1,EP300,ESR1,FOXO1,HMGA1,HMGB1,HNRNPK,HOMER3,HSF1,MAPK1,MAPK3,MED23,MYB,MYC,NFKB1,NOLC1,NR3C1,PTGES2,RB1,RELA,RPS6KA1,RPS6KA5,RUNX1,RUNX2,SMAD3,SMAD4,SMARCA4,SMARCB1,SMARCC1,SP1,SPI1,SPIB,SRF,STAT5A,STAT6,TAF9,TRIM28,AR,Atf2,CDK8,CEBPA,CEBPD,CEBPG,CREB1,DDIT3,EGFR,EGR1,EP300,ESR1,FOXO1,HMGA1,HNRNPK,HSF1,MAPK1,MED23,MED26,MYB,MYC,NFKB1,NOLC1,NR3C1,RARB,RB1,RELA,RUNX1,SMAD3,SMAD4,SMARCA2,SMARCC1,SP1,SPI1,SRF,TRIM28
Protein Size: 345 - Molecular Weight
- 36 kDa
- Gene ID
- 1051
- NCBI Accession
- NM_005194, NP_005185
- UniProt
- P17676
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