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Charged Multivesicular Body Protein 4A (CHMP4A) (C-Term) Peptide

CHMP4A Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN974929

Quick Overview for Charged Multivesicular Body Protein 4A (CHMP4A) (C-Term) Peptide (ABIN974929)

Target

CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    ELEQEELAQE LLNVGDKEEE PSVKLPSVPS THLPAGPAPK VDEDEEALKQ

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-CHMP4A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CHMP4A (Charged Multivesicular Body Protein 4A (CHMP4A))

    Background

    CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression

    Alias Symbols: C14orf123, CHMP4, CHMP4B, FLJ61658, HSPC134, MGC142093, MGC142095, SNF7, SNF7-1, Shax2, VPS32A, SHAX2, VPS32-1

    Protein Interaction Partner: PDCD6IP,PDCD6IP,VPS4A,CC2D1A,CDK13,CHMP4A,CHMP4B,CHMP4C,CHMP5,CHMP6,PDCD6IP,SYT17,TTC19,VPS4A,STAMBP,SYT17

    Protein Size: 265

    Molecular Weight

    29 kDa

    Gene ID

    29082

    NCBI Accession

    NM_014169, NP_054888

    UniProt

    Q14D22
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