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Clock Homolog (Mouse) (CLOCK) (N-Term) Peptide

CLOCK Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN975085
  • Target See all CLOCK products
    CLOCK (Clock Homolog (Mouse) (CLOCK))
    Protein Region
    N-Term
    Origin
    Human, Mouse
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CLOCK antibody (Catalog #: ARP33730_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CLOCK (Clock Homolog (Mouse) (CLOCK))
    Background
    CLOCK is a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: KAT13D, KIAA0334, bHLHe8

    Protein Interaction Partner: ARNTL,ARNTL2,PER3,ARNTL,ARNTL2,EP300,KAT2B,RARA,RXRA

    Protein Size: 846
    Molecular Weight
    95 kDa
    Gene ID
    9575
    NCBI Accession
    NM_004898, NP_004889
    UniProt
    O15516
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