Cereblon (CRBN) (N-Term) Peptide
Quick Overview for Cereblon (CRBN) (N-Term) Peptide (ABIN975278)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- GNHLPLLPAE SEEEDEMEVE DQDSKEAKKP NIINFDTSLP TSHTYLGADM
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CRBN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CRBN (Cereblon (CRBN))
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Background
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This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CRBN,AD-006,
Protein Size: 442 -
Molecular Weight
- 50 kDa
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Gene ID
- 51185
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NCBI Accession
- NP_057386
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UniProt
- Q96SW2
Target
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