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Cereblon (CRBN) (N-Term) Peptide

CRBN Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975278

Quick Overview for Cereblon (CRBN) (N-Term) Peptide (ABIN975278)

Target

CRBN (Cereblon (CRBN))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    GNHLPLLPAE SEEEDEMEVE DQDSKEAKKP NIINFDTSLP TSHTYLGADM

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-CRBN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CRBN (Cereblon (CRBN))

    Background

    This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CRBN,AD-006,

    Protein Size: 442

    Molecular Weight

    50 kDa

    Gene ID

    51185

    NCBI Accession

    NP_057386

    UniProt

    Q96SW2
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