CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) Peptide
CTCFL
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975412
Quick Overview for CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) Peptide (ABIN975412)
Target
CTCFL
(CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CTCFL antibody (Catalog #: ARP36128_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
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Background
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CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BORIS, CTCF-T, MGC163358, dJ579F20.2, CT27, HMGB1L1
Protein Interaction Partner: BRCA1
Protein Size: 663 -
Molecular Weight
- 76 kDa
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Gene ID
- 140690
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NCBI Accession
- NM_080618, NP_542185
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UniProt
- Q8NI51
Target
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