Cathepsin K (CTSK) (Middle Region) Peptide
CTSK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975444
Quick Overview for Cathepsin K (CTSK) (Middle Region) Peptide (ABIN975444)
Target
Cathepsin K (CTSK)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CTSK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Cathepsin K (CTSK) peptide
CTSK Reactivity: Human, Cow, Dog, Mouse, Rat, Pig Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Cathepsin K (CTSK)
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Background
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The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Alias Symbols: CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD
Protein Interaction Partner: FGFR3,KNG1,SERPINB13,SERPINB3,SPARC,FGFR3,SERPINB3
Protein Size: 329 -
Molecular Weight
- 37 kDa
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Gene ID
- 1513
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NCBI Accession
- NM_000396, NP_000387
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UniProt
- P43235
Target
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