Chemokine (C-X-C Motif) Receptor 6 (CXCR6) Peptide
CXCR6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975480
Quick Overview for Chemokine (C-X-C Motif) Receptor 6 (CXCR6) Peptide (ABIN975480)
Target
CXCR6
(Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CXCR6 antibody (Catalog #: AVARP07030_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Chemokine (C-X-C Motif) Receptor 6 (CXCR6) peptide (Ovalbumin)
CXCR6 Reactivity: Human Host: Synthetic WB, Imm, SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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Background
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CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung.
Alias Symbols: BONZO, CD186, STRL33, TYMSTR
Protein Interaction Partner: CXCL16
Protein Size: 342 -
Molecular Weight
- 39 kDa
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Gene ID
- 10663
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NCBI Accession
- NM_006564, NP_006555
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UniProt
- O00574
Target
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