Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2) (C-Term) Peptide
AWAT2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975741
Quick Overview for Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2) (C-Term) Peptide (ABIN975741)
Target
AWAT2
(Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DGAT2L4 antibody (Catalog #: ARP44425_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AWAT2 (Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2))
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Background
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DGAT2L4 is acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. It has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. DGAT2L4 may also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters, however this activity is unclear in vivo.
Alias Symbols: AWAT2, DC4, MFAT, WS, DGAT2L4
Protein Size: 333 -
Molecular Weight
- 38 kDa
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Gene ID
- 158835
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NCBI Accession
- NM_001002254, NP_001002254
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UniProt
- Q6E213
Target
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