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Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2) (C-Term) Peptide

AWAT2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975741
  • Target See all AWAT2 products
    AWAT2 (Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DGAT2L4 antibody (Catalog #: ARP44425_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    AWAT2 (Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2))
    Background
    DGAT2L4 is acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. It has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. DGAT2L4 may also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters, however this activity is unclear in vivo.

    Alias Symbols: AWAT2, DC4, MFAT, WS, DGAT2L4

    Protein Size: 333
    Molecular Weight
    38 kDa
    Gene ID
    158835
    NCBI Accession
    NM_001002254, NP_001002254
    UniProt
    Q6E213
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