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DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16) (N-Term) Peptide

DHX16 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975776
  • Target See all DHX16 products
    DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    RREYLAKRER EKLEDLEAEL ADEEFLFGDV ELSRHERQEL KYKRRVRDLA
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DHX16 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))
    Background
    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: DBP2, DDX16, PRO2014, PRP8, PRPF2, Prp2

    Protein Interaction Partner: COIL,MEGF10,SRRM1,SRRM2,TADA2A

    Protein Size: 981
    Molecular Weight
    107 kDa
    Gene ID
    8449
    NCBI Accession
    NM_001164239, NP_001157711
    UniProt
    B4DZ28
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