Disrupted in Schizophrenia 1 (DISC1) Peptide
DISC1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975802
Quick Overview for Disrupted in Schizophrenia 1 (DISC1) Peptide (ABIN975802)
Target
DISC1
(Disrupted in Schizophrenia 1 (DISC1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DISC1 antibody (Catalog #: ARP47934_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Disrupted in Schizophrenia 1 (DISC1) peptide
DISC1 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
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Background
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DISC1 is a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins.This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1,11)(q42.1,q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: KIAA0457, SCZD9, C1orf136
Protein Interaction Partner: ACTN2,ANKHD1,ATF4,ATF5,ATF7IP,EIF3H,ITSN1,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,TRAF3IP1,ACTN2,ATF4,ATF5,ATF7IP,CCDC141,CIT,DISC1,EIF3H,FEZ1,ITSN1,KCNQ5,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,SYNE1,TRAF3IP1,YWHAG,ACTN2,ATF4,ATF4,ATF5,ATF7IP,CCDC141,CEP290,CEP63,CIT,COL4A1,EIF3A,EIF3H,EPB49,FEZ1,GOLGA2,IMMT,ITSN1,KALRN,KATNAL1,KCNQ5,KIAA1377,MAP1A,MGAT3,MYO1A,NDE1,NDEL1,PPFIA4,RANBP9,RASSF7,SMARCE1,SPTAN1,SPTBN4,SYNE1,TRAF3IP1,YWHAG
Protein Size: 369 -
Molecular Weight
- 38 kDa
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Gene ID
- 27185
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NCBI Accession
- NM_001012958, NP_001012976
Target
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