Disrupted in Schizophrenia 1 (DISC1) Peptide
DISC1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975803
Quick Overview for Disrupted in Schizophrenia 1 (DISC1) Peptide (ABIN975803)
Target
DISC1
(Disrupted in Schizophrenia 1 (DISC1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DOT1L antibody (Catalog #: ARP47938_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Disrupted in Schizophrenia 1 (DISC1) peptide
DISC1 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
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Background
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DOT1L is a histone methyltransferase. It methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones.
Alias Symbols: DOT1, KIAA1814, KMT4, SCZD9, C1orf136
Protein Interaction Partner: ACTN2,ANKHD1,ATF4,ATF5,ATF7IP,EIF3H,ITSN1,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,TRAF3IP1,ACTN2,ATF4,ATF5,ATF7IP,CCDC141,CIT,DISC1,EIF3H,FEZ1,ITSN1,KCNQ5,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,SYNE1,TRAF3IP1,YWHAG,ACTN2,ATF4,ATF4,ATF5,ATF7IP,CCDC141,CEP290,CEP63,CIT,COL4A1,EIF3A,EIF3H,EPB49,FEZ1,GOLGA2,IMMT,ITSN1,KALRN,KATNAL1,KCNQ5,KIAA1377,MAP1A,MGAT3,MYO1A,NDE1,NDEL1,PPFIA4,RANBP9,RASSF7,SMARCE1,SPTAN1,SPTBN4,SYNE1,TRAF3IP1,YWHAG
Protein Size: 1537 -
Molecular Weight
- 165 kDa
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Gene ID
- 27185
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NCBI Accession
- NM_032482, NP_115871
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UniProt
- Q8TEK3
Target
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