Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide
DKK2
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN975816
Quick Overview for Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide (ABIN975816)
Target
DKK2
(Dickkopf 2 Homolog (DKK2))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequence
- NGICIPVTES ILTPHIPALD GTRHRDRNHG HYSNHDLGWQ NLGRPHSKMP
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-Dkk2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
Dickkopf 2 Homolog (DKK2) peptide
DKK2 Reactivity: Human, Mouse, Cow, Dog, Rat Host: Synthetic BP, Imm
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- DKK2 (Dickkopf 2 Homolog (DKK2))
-
Background
-
Dkk2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer's disease.
Alias Symbols: -
Protein Size: 259 -
Molecular Weight
- 28 kDa
-
Gene ID
- 56811
-
NCBI Accession
- NM_020265, NP_064661
-
UniProt
- Q9QYZ8
Target
-
You are here:
