Dihydrolipoyl Transacetylase (DLAT) Peptide
DLAT
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all DLAT products
- DLAT (Dihydrolipoyl Transacetylase (DLAT))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DLAT antibody (Catalog #: ARP41994_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DLAT (Dihydrolipoyl Transacetylase (DLAT))
- Background
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DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC, EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC, MIM 109720) show autoantibodies to DLAT.[supplied by OMIM].
Alias Symbols: DLTA, PDC-E2, PDCE2
Protein Interaction Partner: PDHA1,PDHX,PDK1,PDK2,PDK3,PDK4,PDHB,PDHX,PDK1,PDK2,PDK3
Protein Size: 647 - Molecular Weight
- 71 kDa
- Gene ID
- 1737
- NCBI Accession
- NM_001931, NP_001922
- UniProt
- P10515
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