Diphthamide Biosynthesis Protein 2 (DPH2) (N-Term) Peptide
DPH2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975967
Quick Overview for Diphthamide Biosynthesis Protein 2 (DPH2) (N-Term) Peptide (ABIN975967)
Target
DPH2
(Diphthamide Biosynthesis Protein 2 (DPH2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DPH2 antibody (Catalog #: ARP51957_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))
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Background
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DPH2 gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DPH2L2
Protein Size: 489 -
Molecular Weight
- 52 kDa
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Gene ID
- 1802
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NCBI Accession
- NM_001384, NP_001375
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UniProt
- Q9BQC3
Target
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