E2F Transcription Factor 1 (E2F1) Peptide
E2F1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all E2F1 products
- E2F1 (E2F Transcription Factor 1 (E2F1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-E2F1 antibody (Catalog #: AVARP04006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- E2F1 (E2F Transcription Factor 1 (E2F1))
- Background
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The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Alias Symbols: RBP3, E2F-1, RBAP1, RBBP3
Protein Interaction Partner: E2F2,E2F4,RBL2,BARD1,BIRC5,BRCA1,CBX5,CCDC76,CCNA1,CCNA2,CDC25A,CDC6,CDK1,CDKN2A,CEBPD,CEBPE,CHEK1,CSDA,E2F1,EAPP,FHL2,GAB2,GAS2L1,HIST1H2AG,HIST1H2BJ,HIST2H4A,JMY,MAD2L1,MAD2L1,MDM4,MFAP1,MLH1,MSH2,MSH2,MT1G,MYBL2,MYC,NCOA3,PPP1R13B,PPP1R13B,PRR11,RAD51,RAD54L,RB1,RB1,RB1,RB1,RB1,RB1,RBL1,RBL2,RECQL,TFDP1,TP53BP2,TP53BP2,TP53INP1,TTK,TYMS,UXT,ARID3A,ATM,ATR,BRCA1,BRD2,CCNA1,CCNA2,CDK1,CDK3,CDK7,CDKN2A,CEBPE,CHEK2,CREBBP,CTDP1,CUL1,DDB2,E2F6,GTF2H1,KAT5,MDM4,MNAT1,NCOA3,NCOA6,NDN,NFKB1,NPDC1,PARP1,PHB,PURA,RB1,SERTAD2,SKP2,SP1,SP2,SP3,SP4,TFDP1,TFDP2,TOPBP1,TP53,TP53BP1,TRRAP,ARID3A,BRD2,CCNA1,CCNA2,CDK2,CDK7,CDT1,CREBBP,CUL1,DNMT1,FHL2,GSK3B,GTF2H1,HDAC1,MDM4,MGA,MYBL2,NCOA6,NDN,NDNL2,NFKB1,NPDC1,Nfkb1,PHB,PKIB,PURA,RB1,RBBP4,RBL1,RING1,RNF144A,SKP2,SP1,SP2,SP3,SP4,SPIB,Sp1,TEAD3,TFDP1,TFDP2,TOPBP1,TP53BP1,TRRAP,UBC
Protein Size: 437 - Molecular Weight
- 47 kDa
- Gene ID
- 1869
- NCBI Accession
- NM_005225, NP_005216
- UniProt
- Q01094
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