Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) Peptide
ECT2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976120
Quick Overview for Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) Peptide (ABIN976120)
Target
ECT2
(Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ECT2 antibody (Catalog #: ARP52382_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))
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Background
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ECT2 is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of ECT2 is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ10461, MGC138291, ARHGEF31
Protein Interaction Partner: CDK1,F2RL2,KLHL20,PARD6A,PLK1,RHOG,KLHL20,PARD3,PARD6A,PRKCZ
Protein Size: 883 -
Molecular Weight
- 100 kDa
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Gene ID
- 1894
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NCBI Accession
- NM_018098, NP_060568
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UniProt
- Q9H8V3
Target
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