Endothelial Differentiation Related Factor 1 (EDF1) (Middle Region) Peptide
EDF1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB, IF, IHC
Catalog No. ABIN976130
Quick Overview for Endothelial Differentiation Related Factor 1 (EDF1) (Middle Region) Peptide (ABIN976130)
Target
EDF1
(Endothelial Differentiation Related Factor 1 (EDF1))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-EDF1 antibody (Catalog #: ARP38383_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EDF1 (Endothelial Differentiation Related Factor 1 (EDF1))
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Background
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EDF1 encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene. This gene encodes a protein that may regulate endothelial cell differentiation. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. This protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Two alternatively spliced transcripts which encode distinct proteins have been found for this gene.
Alias Symbols: EDF-1, MBF1, MGC9058
Protein Interaction Partner: ATF1,ATF2,CALM1,CALM3,CALM3,CREB1,NR1H3,NR5A1,NR5A2,PPARG,PRKCA,RXRA,TAF1,TBP,NR1H3,NR5A1,NR5A2,PPARG,RXRA,TBP
Protein Size: 148 -
Molecular Weight
- 16 kDa
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Gene ID
- 8721
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NCBI Accession
- NM_003792, NP_003783
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UniProt
- O60869
Target
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