Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) (N-Term) Peptide
EEF1E1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EEF1E1 products
- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IPVLQTNNGP SLTGLTTIAA HLVKQANKEY LLGSTAEEKA IVQQWLEYRV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EEF1E1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
- Background
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This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
Alias Symbols: AIMP3, P18
Protein Interaction Partner: ATM,ATR,ATM,ATR
Protein Size: 174 - Molecular Weight
- 19 kDa
- Gene ID
- 9521
- NCBI Accession
- NM_004280, NP_004271
- UniProt
- O43324
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