Estrogen Receptor 2 (ESR2) (Middle Region) Peptide
ESR2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ESR2 products
- ESR2 (Estrogen Receptor 2 (ESR2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ESR2 antibody (Catalog #: ARP32258_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ESR2 (Estrogen Receptor 2 (ESR2))
- Background
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ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. It contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Alias Symbols: ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
Protein Interaction Partner: BCAS2,ESR1,MAD2L1,PRMT2,AKAP13,AKT1,BCAS2,CALM1,CALM3,CALM3,DDX54,DNTTIP2,ESR1,ESR2,MAD2L1,MAPK11,MED1,MKNK2,MMS19,NCOA1,NCOA3,NCOA6,NCOA7,NCOR1,NCOR2,NR0B1,NR0B2,NRIP1,OXT,PIAS1,PIAS3,PNRC1,PNRC2,PPARGC1A,PRMT2,PSMC3IP,RBM39,RBM9,REXO4,SMAD2,SMAD3,SMAD4,SMARCE1,SP1,SRC,SREBF1,STAT5A,TRIM24,TRIM59,WIPI1,YWHAH,ZBTB17,CCNC,CDK8,DAP3,DDX17,DDX5,DDX54,DNTTIP2,ESR1,MAD2L1,MED1,MED10,MED12,MED14,MED16,MED17,MED20,MED21,MED23,MED24,MED6,MED7,MKNK2,NCOA1,NCOA3,NCOA6,PIAS2,RBM39,RBM9,REXO4,SMARCE1,SRC,STAT5A,UBC,UBE3A,YWHAQ
Protein Size: 530 - Molecular Weight
- 59 kDa
- Gene ID
- 2100
- NCBI Accession
- NM_001437, NP_001428
- UniProt
- Q92731
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