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Exonuclease 1 (EXO1) (N-Term) Peptide

EXO1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976503

Quick Overview for Exonuclease 1 (EXO1) (N-Term) Peptide (ABIN976503)

Target

Exonuclease 1 (EXO1)

Origin

Human

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    ILVFDGCTLP SKKEVERSRR ERRQANLLKG KQLLREGKVS EARECFTRSI

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-EXO1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Exonuclease 1 (EXO1)

    Background

    This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

    Alias Symbols: HEX1, hExoI

    Protein Interaction Partner: MLH1,MSH2,MLH1,MSH2,MSH3,PCNA,PMS2,MLH1,MSH2,MSH3,PMS2,ATM,BLM,MLH1,MSH2,MSH3,PMS1,PMS2,YWHAB,YWHAE,YWHAZ

    Protein Size: 803

    Molecular Weight

    89 kDa

    Gene ID

    9156

    NCBI Accession

    NM_003686, NP_003677

    UniProt

    Q9UQ84
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