Family with Sequence Similarity 120A (FAM120A) (Middle Region) Peptide
FAM120A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FAM120A products
- FAM120A (Family with Sequence Similarity 120A (FAM120A))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FAM120A antibody (Catalog #: ARP55089_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FAM120A (Family with Sequence Similarity 120A (FAM120A))
- Background
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FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Alias Symbols: C9orf10, DNAPTP1, DNAPTP5, MGC111527, MGC133257, OSSA
Protein Size: 1118 - Molecular Weight
- 122 kDa
- Gene ID
- 23196
- NCBI Accession
- NM_014612, NP_055427
- UniProt
- Q9NZB2
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