F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptide
FBXL3
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN976718
Quick Overview for F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) (C-Term) Peptide (ABIN976718)
Target
FBXL3
(F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Fbxl3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) peptide
FBXL3 Reactivity: Human, Mouse, Dog, Pig, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
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Background
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Fbxl3 is a substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Alias Symbols: AU041772, AW212966, FBK, Fbl3a, Fbxl3a, Ovtm
Protein Size: 428 -
Molecular Weight
- 49 kDa
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Gene ID
- 50789
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NCBI Accession
- NM_015822, NP_056637
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UniProt
- Q8C4V4
Target
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