F-Box Protein 31 (FBXO31) (Middle Region) Peptide
FBXO31
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976747
Quick Overview for F-Box Protein 31 (FBXO31) (Middle Region) Peptide (ABIN976747)
Target
FBXO31
(F-Box Protein 31 (FBXO31))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequence
- QGPRESQPSP AQPRAEAPSK GPDGTPGEDG GEPGDAVAAA EQPAQCGQGQ
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-FBXO31 Antibody(ARP53775_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- FBXO31 (F-Box Protein 31 (FBXO31))
-
Background
-
FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
Protein Interaction Partner: CUL1,RBX1,SKP1
Protein Size: 367 -
Molecular Weight
- 40 kDa
-
Gene ID
- 79791
-
NCBI Accession
- NM_024735, NP_079011
-
UniProt
- Q5XUX0
Target
-
You are here:
