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F-Box Protein 7 (FBXO7) (Middle Region) Peptide

FBXO7 Reactivity: Human Host: Synthetic BP, WB, IP
Catalog No. ABIN976761

Quick Overview for F-Box Protein 7 (FBXO7) (Middle Region) Peptide (ABIN976761)

Target

FBXO7 (F-Box Protein 7 (FBXO7))

Origin

Human

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunoprecipitation (IP)
  • Protein Region

    Middle Region

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-FBXO7 antibody (Catalog #: ARP43128_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    FBXO7 (F-Box Protein 7 (FBXO7))

    Background

    FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

    Alias Symbols: DKFZp686B08113, FBX, FBX07, FBX7, PKPS, PARK15

    Protein Interaction Partner: SKP1,SKP1,BIRC3,ELF4,SKP1,CDC34,CDK6,COPS6,CUL1,PSMF1,SKP1,UBE2D2

    Protein Size: 522

    Molecular Weight

    58 kDa

    Gene ID

    25793

    NCBI Accession

    NM_012179, NP_036311

    UniProt

    Q9Y3I1
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