FK506 Binding Protein 3, 25kDa (FKBP3) Peptide
FKBP3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976872
$160.46
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100 μg
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Quick Overview for FK506 Binding Protein 3, 25kDa (FKBP3) Peptide (ABIN976872)
Target
FKBP3
(FK506 Binding Protein 3, 25kDa (FKBP3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-FKBP3 antibody (Catalog #: ARP54612_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
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Background
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FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Alias Symbols: FKBP-25, PPIase, FKBP-3, FKBP25
Protein Interaction Partner: CSNK2A1,CSNK2A2,CSNK2B,HDAC1,HDAC2,YY1,HDAC1,HDAC2,MDM2,MTA2,TP53,YY1
Protein Size: 224 -
Molecular Weight
- 25 kDa
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Gene ID
- 2287
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NCBI Accession
- NM_002013, NP_002004
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UniProt
- Q00688
Target
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