Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (C-Term) Peptide
FRS3
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN977104
Quick Overview for Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (C-Term) Peptide (ABIN977104)
Target
FRS3
(Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- APGPTPHPVR SSDSYAVIDL KKTAAMSDLQ RALPRDDGAV RKTRHNSTDL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Frs3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
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Background
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Frs3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. It is involved in the activation of MAP kinases. Frs3 Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Alias Symbols: 4930417B13Rik, AI449674, Frs2beta, MGC25496, Snt2
Protein Size: 492 -
Molecular Weight
- 54 kDa
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Gene ID
- 107971
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NCBI Accession
- NM_144939, NP_659188
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UniProt
- Q91WJ0
Target
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