X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Peptide
XRCC6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977179
Quick Overview for X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) Peptide (ABIN977179)
Target
XRCC6
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-G22P1 antibody (Catalog #: ARP34116_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
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Background
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The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Alias Symbols: ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Protein Interaction Partner: BARD1,CBX5,CCNA1,CLU,TP53,WRN,XRCC5,ABCD4,ABL1,ACD,APEX1,AR,ARAP1,ATP6V1E1,BARD1,C9orf46,CBX5,CCNA1,CCT3,CD40,CDCA5,CDKN1A,CHEK1,CLTC,CLU,DNTT,EGFR,FMNL1,GAL3ST4,HN1L,HOXC4,HSF1,HTT,ILVBL,KAT2A,KIAA0182,MAPK8,MRE11A,MSX2,NAA15,NCF4,NCOA6,NHP2L1,NIT1,NOTCH1,PAEP,PAFAH1B3,PARP1,PCNA,PECAM1,PGAM1,PGR,POR,POU2F1,POU2F2,PRKDC,PTTG1,RBBP4,RPLP1,RRAS2,RUNX2,SERPINB9,SGOL1,SKIL,SMAD3,SMAD7,SNTA1,TBCD,TCF4,TERF2,TERT,TP53,VAV1,WRN,XRCC5,XRCC6BP1,YWHAZ,ABCD4,ABL1,ACD,AR,ARAP1,ATP6V1E1,BIN1,C9orf46,CBX5,CCNA1,CD40,CDCA5,CDK2,CHEK1,CLU,CREBBP,DHX9,DLX2,DNTT,FCHSD1,FMNL1,GAL3ST4,Gm899,HOXC4,HOXD4,HSF1,ILVBL,KAT2A,KIAA0182,MRE11A,NCF4,NCOA6,NHP2L1,NIT1,NOTCH1,PAEP,PAFAH1B3,PCNA,PECAM1,PGAM1,POU2F1,POU2F2,PRKDC,PTTG1,RBBP4,RPA2,RPLP1,RRAS2,SERPINB9,SIRT6,SNTA1,TAL1,TBCD,TERF2,TERF2IP,TERT,VAV1,WRN,XRCC5,XRCC6BP1,YWHAZ
Protein Size: 609 -
Molecular Weight
- 70 kDa
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Gene ID
- 2547
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NCBI Accession
- NM_001469, NP_001460
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UniProt
- Q6FG89
Target
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