gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (N-Term) Peptide
GABRG2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977220
Quick Overview for gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (N-Term) Peptide (ABIN977220)
Target
GABRG2
(gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GABRG2 antibody (Catalog #: AVARP13033_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
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Background
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GABRG2 is a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: CAE2, ECA2, GEFSP3
Protein Interaction Partner: DRD5,GABARAP,GABRG2,PPP3CA,PRKCA,PRKCB,ZDHHC3,DRD5,GABARAP
Protein Size: 467 -
Molecular Weight
- 50 kDa
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Gene ID
- 2566
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NCBI Accession
- NM_000816, NP_000807
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UniProt
- Q5REA1
Target
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