Galanin Receptor 1 (GALR1) (C-Term) Peptide
GALR1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977261
Quick Overview for Galanin Receptor 1 (GALR1) (C-Term) Peptide (ABIN977261)
Target
Galanin Receptor 1 (GALR1)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- CLAYSNSSVN PIIYAFLSEN FRKAYKQVFK CHIRKDSHLS DTKESKSRID
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GALR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Galanin Receptor 1 (GALR1)
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Background
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The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
Alias Symbols: GALNR, GALNR1
Protein Interaction Partner: GAL
Protein Size: 349 -
Molecular Weight
- 38 kDa
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Gene ID
- 2587
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NCBI Accession
- NM_001480, NP_001471
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UniProt
- P47211
Target
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