Galanin Receptor 1 (GALR1) (C-Term) Peptide
GALR1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Galanin Receptor 1 (GALR1) products
- Galanin Receptor 1 (GALR1)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CLAYSNSSVN PIIYAFLSEN FRKAYKQVFK CHIRKDSHLS DTKESKSRID
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GALR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Galanin Receptor 1 (GALR1)
- Background
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The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
Alias Symbols: GALNR, GALNR1
Protein Interaction Partner: GAL
Protein Size: 349 - Molecular Weight
- 38 kDa
- Gene ID
- 2587
- NCBI Accession
- NM_001480, NP_001471
- UniProt
- P47211
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