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Geranylgeranyl Diphosphate Synthase 1 (GGPS1) (Middle Region) Peptide

GGPS1 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN977384

Quick Overview for Geranylgeranyl Diphosphate Synthase 1 (GGPS1) (Middle Region) Peptide (ABIN977384)

Target

GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein Region

    Middle Region

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-GGPS1 antibody (Catalog #: ARP48534_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

    Background

    GGPS1 is a member of the prenyltransferase family and has geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. The protein is an important precursor of carotenoids and geranylated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: GGPPS, GGPPS1

    Protein Size: 300

    Molecular Weight

    35 kDa

    Gene ID

    9453

    NCBI Accession

    NM_001037277, NP_001032354

    UniProt

    O95749
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