Gastric Inhibitory Polypeptide Receptor (GIPR) (N-Term) Peptide
GIPR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GIPR products
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GFVLRQCGSD GQWGLWRDHT QCENPEKNEA FLDQRLILER LQVMYTVGYS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GIPR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Background
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This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Alias Symbols: MGC126722, PGQTL2
Protein Interaction Partner: GIP,UBC
Protein Size: 466 - Molecular Weight
- 53 kDa
- Gene ID
- 2696
- NCBI Accession
- NM_000164, NP_000155
- UniProt
- P48546
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