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Gastrin-Releasing Peptide (GRP) (C-Term) Peptide

GRP Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN977703

Quick Overview for Gastrin-Releasing Peptide (GRP) (C-Term) Peptide (ABIN977703)

Target

Gastrin-Releasing Peptide (GRP)

Origin

Human

Source

  • 5
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    C-Term

    Sequence

    ENRNHQPPQP KALGNQQPSW DSEDSSNFKD VGSKGKGSQR EGRNPQLNQQ

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-GRP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Gastrin-Releasing Peptide (GRP)

    Background

    This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: BN, GRP-10, preproGRP, proGRP

    Protein Interaction Partner: DPP4,GRPR,MEP1A,MEP1B

    Protein Size: 141

    Molecular Weight

    15 kDa

    Gene ID

    2922

    NCBI Accession

    NM_001012512, NP_001012530
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