Gelsolin (GSN) Peptide
GSN
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN977721
Quick Overview for Gelsolin (GSN) Peptide (ABIN977721)
Target
Gelsolin (GSN)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GSN antibody (Catalog #: ARP54299_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Gelsolin (GSN) (AA 655-666) peptide (Ovalbumin)
GSN Reactivity: Human Host: Synthetic Imm, WB, SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Gelsolin (GSN)
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Background
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GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Alias Symbols: DKFZp313L0718, ADF, AGEL
Protein Interaction Partner: tax,ACTA1,ACTB,ACTG1,ACTN4,APP,AR,BCAR1,CASP3,CLIC5,CSK,FHIT,FN1,LIMK2,PIK3CG,PTK2B,PXN,TNIK,TOM1L1,VASP,VCL,VDAC1,ACTA1,ACTN4,APP,AR,CASP4,FN1,PIK3CA,PLCG1,PPM1B,PTK2,PTK2B,PTPN12,PXN,SRC,STK39,TOM1L1,VCL,VDAC1
Protein Size: 782 -
Molecular Weight
- 83 kDa
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Gene ID
- 2934
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NCBI Accession
- NM_000177, NP_000168
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UniProt
- P06396
Target
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