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General Transcription Factor IIB (GTF2B) Peptide

GTF2B Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN977751
  • Target See all GTF2B products
    GTF2B (General Transcription Factor IIB (GTF2B))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-GTF2B antibody (Catalog #: P100990_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GTF2B (General Transcription Factor IIB (GTF2B))
    Background
    GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.

    Alias Symbols: TF2B, TFIIB

    Protein Interaction Partner: BAX,EP300,POU3F2,THRA,UL48,VDR,BCL3,CREBBP,DHX9,EP300,ESR1,ESRRA,FOXF2,GTF2B,GTF2E1,GTF2E2,GTF2F1,GTF2F2,HSF1,IKZF1,JUN,MCM2,NCOA1,NCOA3,NCOA4,NOLC1,NR2F1,NR5A1,POLR2A,POU3F2,PSMC2,PSMC5,REL,RELA,TAF9,TBP,TBPL1,TCEA2,THRA,TRAM2,VDR,ATF4,BCL3,CREBBP,CTBP1,CTDP1,DHX9,FOXF2,GTF2E1,GTF2E2,GTF2F1,GTF2F2,GTF2H4,HSF1,HSF1,IKZF1,JUN,KLF5,MECP2,MED21,MYC,NCOA1,NCOA4,NR2F1,NR5A1,PKP2,POLR2A,POLR2H,POLR2J,POLR3A,PSMC2,REL,RELA,TAF11,TBP,TBPL1,TCEA1

    Protein Size: 316
    Molecular Weight
    35 kDa
    Gene ID
    2959
    NCBI Accession
    NM_001514, NP_001505
    UniProt
    Q00403
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