HMG Box-Containing Protein 1 (HBP1) (Middle Region) Peptide
-
- Target See all HBP1 products
- HBP1 (HMG Box-Containing Protein 1 (HBP1))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HBP1 antibody (Catalog #: ARP38977_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- HBP1 (HMG Box-Containing Protein 1 (HBP1))
- Background
-
HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.
Alias Symbols: FLJ16340
Protein Interaction Partner: EWSR1,HDAC1,KIAA1279,RB1,RBL2,SAP30,SIN3A,SMAD1,TCF4,HDAC1,RB1,RBL2,SIN3A,TCF4
Protein Size: 514 - Molecular Weight
- 58 kDa
- Gene ID
- 26959
- NCBI Accession
- NM_012257, NP_036389
- UniProt
- O60381
-