HMG Box-Containing Protein 1 (HBP1) (Middle Region) Peptide
HBP1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977871
Quick Overview for HMG Box-Containing Protein 1 (HBP1) (Middle Region) Peptide (ABIN977871)
Target
HBP1
(HMG Box-Containing Protein 1 (HBP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HBP1 antibody (Catalog #: ARP38977_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HBP1 (HMG Box-Containing Protein 1 (HBP1))
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Background
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HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.
Alias Symbols: FLJ16340
Protein Interaction Partner: EWSR1,HDAC1,KIAA1279,RB1,RBL2,SAP30,SIN3A,SMAD1,TCF4,HDAC1,RB1,RBL2,SIN3A,TCF4
Protein Size: 514 -
Molecular Weight
- 58 kDa
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Gene ID
- 26959
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NCBI Accession
- NM_012257, NP_036389
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UniProt
- O60381
Target
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