Hect Domain and RLD 4 (HERC4) (Middle Region) Peptide
HERC4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN977934
Quick Overview for Hect Domain and RLD 4 (HERC4) (Middle Region) Peptide (ABIN977934)
Target
HERC4
(Hect Domain and RLD 4 (HERC4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- VGCGLRHTVF VLDDGTVYTC GCNDLGQLGH EKSRKKPEIL KVCQISRLYR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HERC4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HERC4 (Hect Domain and RLD 4 (HERC4))
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Background
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HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.
Alias Symbols: DKFZp564G092, KIAA1593
Protein Interaction Partner: HERC6
Protein Size: 117 -
Molecular Weight
- 13 kDa
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Gene ID
- 26091
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NCBI Accession
- NM_001017972, NP_001017972
Target
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