Hexokinase 1 (HK1) (Middle Region) Peptide
HK1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Hexokinase 1 (HK1) products
- Hexokinase 1 (HK1)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ILVKMAKEGL LFEGRITPEL LTRGKFNTSD VSAIEKNKEG LHNAKEILTR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Hexokinase 1 (HK1)
- Background
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alias Symbols: HK1-ta, HK1-tb, HK1-tc, HKI, HXK1
Protein Interaction Partner: ENO2,SCMH1,VDAC1,VDAC2,C12orf44,ENO2,GBAS
Protein Size: 921 - Molecular Weight
- 103 kDa
- Gene ID
- 3098
- NCBI Accession
- NM_033498, NP_277033
- UniProt
- P19367
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