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HLA Class I alpha F (HLAF) (N-Term) Peptide

HLAF Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN978029

Quick Overview for HLA Class I alpha F (HLAF) (N-Term) Peptide (ABIN978029)

Target

HLA-F (HLAF) (HLA Class I alpha F (HLAF))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Sequence

PWVEQEGPQY WEWTTGYAKA NAQTDRVALR NLLRRYNQSE AGSHTLQGMN

Characteristics

This is a synthetic peptide designed for use in combination with anti-HLA-F Antibody(ARP49410_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
HLA Class I alpha F (HLAF) peptide
HLAF Host: Synthetic BP, WB, IHC

HLA Class I alpha F (HLAF) peptide
HLAF Reactivity: Mammalian Host: Synthetic BP, WB, IHC

HLA Class I alpha F (HLAF) peptide
HLAF Reactivity: Human Host: Synthetic BP, WB, IHC

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

HLA-F (HLAF) (HLA Class I alpha F (HLAF))

Background

HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation.

Alias Symbols: CDA12, HLA-5.4, HLA-CDA12, HLAF

Protein Interaction Partner: B2M,HLA-F,LILRB1,LILRB2,TAP1,LILRB1,LILRB2

Protein Size: 442

Molecular Weight

48 kDa

Gene ID

3134

NCBI Accession

NM_001098479, NP_001091949

UniProt

Q5JQI8

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