Hook Homolog 1 (HOOK1) (C-Term) Peptide
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- Target See all HOOK1 products
- HOOK1 (Hook Homolog 1 (HOOK1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- REVFIRLQHE NKMLRLQQEG SENERIEELQ EQLEQKHRKM NELETEQRLS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HOOK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HOOK1 (Hook Homolog 1 (HOOK1))
- Background
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This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.
Alias Symbols: HK1, MGC10642
Protein Interaction Partner: ANK3,ZNF250,AKTIP,ZNF250
Protein Size: 728 - Molecular Weight
- 80 kDa
- Gene ID
- 51361
- NCBI Accession
- NM_015888, NP_056972
- UniProt
- Q9UJC3
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