Histamine Receptor H2 (HRH2) (C-Term) Peptide
HRH2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978242
Quick Overview for Histamine Receptor H2 (HRH2) (C-Term) Peptide (ABIN978242)
Target
HRH2
(Histamine Receptor H2 (HRH2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- DFRTGYQQLF CCRLANRNSH KTSLRSNASQ LSRTQSREPR QQEEKPLKLQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HRH2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HRH2 (Histamine Receptor H2 (HRH2))
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Background
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Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: H2R
Protein Size: 359 -
Molecular Weight
- 40 kDa
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Gene ID
- 3274
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NCBI Accession
- NM_022304, NP_071640
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UniProt
- P25021
Target
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