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Histamine Receptor H2 (HRH2) (C-Term) Peptide

HRH2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978242
  • Target See all HRH2 products
    HRH2 (Histamine Receptor H2 (HRH2))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    DFRTGYQQLF CCRLANRNSH KTSLRSNASQ LSRTQSREPR QQEEKPLKLQ
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-HRH2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HRH2 (Histamine Receptor H2 (HRH2))
    Background
    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: H2R

    Protein Size: 359
    Molecular Weight
    40 kDa
    Gene ID
    3274
    NCBI Accession
    NM_022304, NP_071640
    UniProt
    P25021
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