Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Peptide
HSD11B2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN978258
Quick Overview for Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Peptide (ABIN978258)
Target
HSD11B2
(Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HSD11B2 antibody (Catalog #: ARP41372_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
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Background
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HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Alias Symbols: AME, AME1, HSD11K, HSD2, SDR9C3
Protein Size: 44 -
Molecular Weight
- 45 kDa
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Gene ID
- 3291
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NCBI Accession
- NM_000196, NP_000187
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UniProt
- P80365
Target
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