Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (N-Term) Peptide
HSD17B3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HSD17B3 products
- HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AVITGAGDGI GKAYSFELAK RGLNVVLISR TLEKLEAIAT EIERTTGRSV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HSD17B3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))
- Background
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This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
Alias Symbols: EDH17B3, SDR12C2
Protein Size: 310 - Molecular Weight
- 34 kDa
- Gene ID
- 3293
- NCBI Accession
- NM_000197, NP_000188
- UniProt
- P37058
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