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Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (N-Term) Peptide

HSD17B3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978264

Quick Overview for Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3) (N-Term) Peptide (ABIN978264)

Target

HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    AVITGAGDGI GKAYSFELAK RGLNVVLISR TLEKLEAIAT EIERTTGRSV

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-HSD17B3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

    Background

    This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.

    Alias Symbols: EDH17B3, SDR12C2

    Protein Size: 310

    Molecular Weight

    34 kDa

    Gene ID

    3293

    NCBI Accession

    NM_000197, NP_000188

    UniProt

    P37058
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