HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) Peptide
Quick Overview for HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) Peptide (ABIN978337)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HTATIP2 antibody (Catalog #: ARP32774_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
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Target Type
- Viral Protein
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Background
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CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.
Alias Symbols: CC3, TIP30, SDR44U1
Protein Interaction Partner: ETS1,NCOA5
Protein Size: 242 -
Molecular Weight
- 27 kDa
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Gene ID
- 10553
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NCBI Accession
- NM_006410, NP_006401
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UniProt
- O15383
Target
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