5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) Peptide
HTR2A
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN978346
Quick Overview for 5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A) (N-Term) Peptide (ABIN978346)
Target
HTR2A
(5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HTR2A antibody (Catalog #: AVARP13044_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
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Background
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HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Alias Symbols: 5-HT2A, HTR2
Protein Interaction Partner: ANKS1B,DLG4,EIF3F,GLUL,GNA11,GNAI1,GNAQ,JAK2,MAP1A,MRPL28,NDUFB10,NME3,NTRK3,PON2,PPP5C,RPS6KA3,DLG4,JAK2
Protein Size: 471 -
Molecular Weight
- 52 kDa
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Gene ID
- 3356
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NCBI Accession
- NM_000621, NP_000612
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UniProt
- P28223
Target
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