Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Peptide
IGLL1
Reactivity: Human
Host: Synthetic
WB, BP
Catalog No. ABIN978447
Quick Overview for Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) Peptide (ABIN978447)
Target
IGLL1
(Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IGLL1 antibody (Catalog #: ARP42547_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Immunoglobulin lambda-Like Polypeptide 1 (IGLL1) peptide
IGLL1 Reactivity: Mouse Host: Escherichia coli (E. coli) WB, ELISA, IP, SDS Dithiothreitol (DTT)
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
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Background
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The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in its gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made.The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: 14.1, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2, AGM2
Protein Interaction Partner: IGLL1,MYOC
Protein Size: 213 -
Molecular Weight
- 19 kDa
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Gene ID
- 3543
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NCBI Accession
- NM_020070, NP_064455
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UniProt
- P15814
Target
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