Junctional Adhesion Molecule 2 (JAM2) (Middle Region) Peptide
JAM2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all JAM2 products
- JAM2 (Junctional Adhesion Molecule 2 (JAM2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LVAPAVPSCE VPSSALSGTV VELRCQDKEG NPAPEYTWFK DGIRLLENPR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-JAM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- JAM2 (Junctional Adhesion Molecule 2 (JAM2))
- Background
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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
Alias Symbols: C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM
Protein Size: 298 - Molecular Weight
- 31 kDa
- Gene ID
- 58494
- NCBI Accession
- NM_021219, NP_067042
- UniProt
- P57087
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