Karyopherin (Importin) alpha 4 (KPNA4) Peptide
KPNA4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979102
Quick Overview for Karyopherin (Importin) alpha 4 (KPNA4) Peptide (ABIN979102)
Target
KPNA4
(Karyopherin (Importin) alpha 4 (KPNA4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-KPNA4 antibody (Catalog #: ARP54676_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
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Background
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The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. KPNA4 shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IPOA3, MGC12217, MGC26703, QIP1, SRP3
Protein Interaction Partner: TGM2,RECQL,TGM2,ARRB2,CSE1L,KPNB1,RECQL,TGM2
Protein Size: 521 -
Molecular Weight
- 58 kDa
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Gene ID
- 3840
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NCBI Accession
- NM_002268, NP_002259
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UniProt
- O00629
Target
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