Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) (N-Term) Peptide
LIPA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979336
Quick Overview for Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA) (N-Term) Peptide (ABIN979336)
Target
Lipase A (LIPA)
(Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- SYWGFPSEEY LVETEDGYIL CLNRIPHGRK NHSDKGPKPV VFLQHGLLAD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LIPA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
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Background
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This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CESD, LAL
Protein Size: 399 -
Molecular Weight
- 43 kDa
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Gene ID
- 3988
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NCBI Accession
- NM_000235, NP_000226
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UniProt
- P38571
Target
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