Lysyl Oxidase-Like 4 (LOXL4) (Middle Region) Peptide
LOXL4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all LOXL4 products
- LOXL4 (Lysyl Oxidase-Like 4 (LOXL4))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ARGKLRPACP GGMHAVVSCV AGPHFRPPKT KPQRKGSWAE EPRVRLRSGA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LOXL4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LOXL4 (Lysyl Oxidase-Like 4 (LOXL4))
- Background
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This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Alias Symbols: FLJ21889, LOXC
Protein Interaction Partner: COL2A1,TRIP13,TRIP13
Protein Size: 756 - Molecular Weight
- 82 kDa
- Gene ID
- 84171
- NCBI Accession
- NM_032211, NP_115587
- UniProt
- Q96JB6
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